Pipeline

Potential best-in-class anti-CD19 CAR-T product in China
To fully explore the clinical potential of relma-cel, we intend to develop relma-cel for a number of other hematological indications, including FL, MCL, CLL, second line LBCL and ALL
Comprehensive and differentiated cell therapy pipeline covering both hematological cancers and solid tumors
Valued partner in the market with a variety of business development, licensing and acquisition opportunities
- JWCAR129 is an autologous CAR-T product that targets BCMA, which is expressed in MM and is a promising target for CAR-T therapies. Other anti-BCMA CAR-T therapies have demonstrated high response rates and manageable toxicity profiles in patients with r/r MM who have failed up to ten prior lines of therapy.
- Eureka’s ARTEMIS platform is the basis for JWATM203 and JWATM204. It is a novel technology platform intended to create potentially more effective and safer T cell therapies with better tumor infiltration than are currently available.
Fully Integrated Cell Therapy Product Development Platform
The uniquely designed and fully integrated product development capabilities range from translational research and analytical development through process development and clinical development to regulatory affairs, clinical and commercial manufacturing
Information as of: April 2022
Abbreviations: LBCL = large B-cell lymphoma; FL = follicular lymphoma; MCL = mantle cell lymphoma; ALL = acute lymphoblastic leukemia; CLL = chronic lymphocytic leukemia; MM = multiple myeloma; NHL = non-Hodgkin lymphoma; HCC = hepatocellular carcinoma; NSCLC = non-small cell lung cancer; AFP = alpha-fetoprotein; GPC3 = glypican-3; r/r = relapsed or refractory; 3L = third-line; 2L = second-line;Basket=Basket Design, A variety of solid tumors were included
* Mainland China, Hong Kong, Macau and Taiwan refer to Mainland China, Hong Kong (China), Macau (China) and Taiwan (China), respectively.
** Denotes a Core Product Candidate.